BPC-157 (BPC157): research reagent reference

Keep the sealed vial dry, dark and frozen at −20 °C or colder, and colder still (−50 to −80 °C) for long-term storage.^S1 The lyophilised powder is hygroscopic, so let the vial reach room temperature in a desiccator before opening it. The sequence contains none of the cysteine, methionine or tryptophan residues most prone to oxidation, nor the asparagine or glutamine residues prone to deamidation, but solutions are still short-lived: keep a reconstituted stock as frozen single-use aliquots.

BPC-157 carries three acidic residues (one glutamate, two aspartates) and one lysine, a net charge of about −2 at neutral pH, so standard handling guides would class it as an acidic peptide and suggest water or a neutral to slightly basic buffer first.

1. Work in a clean laminar-flow or biosafety cabinet using aseptic technique, with gloves and eye protection.
2. Let the sealed vial reach room temperature in a desiccator before opening, so moisture does not condense on the powder.
3. Tap or briefly centrifuge the vial so all of the powder sits at the bottom.
4. Use the solvent your assay protocol specifies. Sterile water or a suitable buffer suits most short, charged peptides; a sequence that resists dissolving may need the small amount of dilute acetic acid or organic co-solvent described in standard peptide handling guides.^S1
5. Add the solvent slowly down the inside wall of the vial with a calibrated pipette, then swirl or roll gently until the solution is clear. Avoid vigorous shaking or vortexing, which can promote aggregation.
6. If the assay needs a sterile solution, pass it through a 0.22 µm low-protein-binding filter.
7. Label the stock with compound, solvent, date and batch number, split it into single-use aliquots, and freeze them at −20 °C or colder. Thaw one aliquot per experiment and discard what is left rather than refreezing it.

The concentration of a stock solution is set by the assay protocol, not by this page. Our guides to reconstituting peptides with bacteriostatic or sterile water and how to store peptides explain the reasoning behind each step.

Purity: not published. Titan Peptides publishes a purity figure only once a certificate of analysis (COA) for the batch has been checked and its compound name, CAS number and sequence match the product. Until that check is complete, no purity figure is shown on this page or in the catalogue.

A COA is available to account holders on request. Our guide on how to read a peptide certificate of analysis explains what to check, and HPLC and mass spectrometry for peptide purity covers how the figures are measured.

The TGA's safety advisory of 13 April 2026 names BPC-157 as an example of an unapproved peptide product and states that a "research use only" disclaimer does not make its supply lawful.³ BPC-157 is not an approved therapeutic good in Australia. Our guide to research peptides and Australian law explains how scheduling applies.